Sook Ryun Park Selected Research

EZN 2968

2/2014

Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors.

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Sook Ryun Park Research Topics

Disease

61	Stomach Neoplasms (Stomach Cancer) 10/2023 - 11/2004
44	Neoplasms (Cancer) 05/2024 - 12/2003
11	Hepatocellular Carcinoma (Hepatoma) 08/2023 - 11/2016
10	Esophageal Squamous Cell Carcinoma 01/2023 - 09/2019
5	Carcinoma (Carcinomatosis) 04/2016 - 11/2004
4	Neutropenia 11/2023 - 10/2005
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 07/2022 - 01/2003
4	Hemorrhage 01/2022 - 06/2017
4	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 11/2020 - 01/2013
4	Adenocarcinoma 01/2018 - 11/2004
4	Neoplasm Metastasis (Metastasis) 11/2017 - 03/2009
3	Disease Progression 01/2024 - 10/2011
3	Vomiting 11/2023 - 12/2004
3	Venous Thromboembolism 01/2022 - 04/2017
3	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 11/2013
3	Esophageal Neoplasms (Esophageal Cancer) 01/2021 - 11/2014
3	Exanthema (Rash) 11/2020 - 02/2010
3	Hypoxia (Hypoxemia) 08/2014 - 02/2014
2	Cholangiocarcinoma 08/2023 - 01/2021
2	Septic Shock (Toxic Shock Syndrome) 01/2023 - 12/2010
2	Pneumonia (Pneumonitis) 01/2023 - 04/2005
2	Thrombocytopenia (Thrombopenia) 01/2021 - 10/2015
2	Lymphatic Metastasis 04/2018 - 06/2012
2	Abdominal Pain (Pain, Abdominal) 04/2017 - 04/2016
2	Renal Cell Carcinoma (Grawitz Tumor) 03/2015 - 04/2013
2	Gastric Outlet Obstruction 01/2014 - 05/2011
2	Anemia 10/2011 - 09/2004
2	Pathologic Constriction (Stenosis) 07/2010 - 08/2009
1	Nausea 11/2023
1	Microsatellite Instability 10/2023
1	Pulmonary Tuberculosis 01/2023
1	Myocarditis (Carditis) 01/2023
1	Respiratory Insufficiency (Respiratory Failure) 01/2023
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2022
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022

Drug/Important Bio-Agent (IBA)

14	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 11/2004
13	Capecitabine (Xeloda)FDA Link 04/2021 - 04/2005
10	Oxaliplatin (Eloxatin)FDA LinkGeneric 04/2021 - 03/2010
9	Docetaxel (Taxotere)FDA Link 04/2018 - 04/2005
6	Paclitaxel (Taxol)FDA LinkGeneric 10/2023 - 01/2003
6	Sorafenib (BAY 43-9006)FDA Link 09/2021 - 11/2016
5	NivolumabIBA 01/2024 - 07/2020
5	Biomarkers (Surrogate Marker)IBA 10/2023 - 03/2015
5	Fluorouracil (Carac)FDA LinkGeneric 01/2018 - 10/2005
4	Immune Checkpoint InhibitorsIBA 08/2023 - 01/2020
4	Proteins (Proteins, Gene)FDA Link 07/2022 - 02/2014
4	Bevacizumab (Avastin)FDA Link 04/2021 - 10/2011
4	Trastuzumab (Herceptin)FDA Link 04/2021 - 03/2015
4	EnzymesIBA 01/2021 - 08/2014
4	Imatinib Mesylate (Gleevec)FDA Link 11/2020 - 01/2013
3	Cell-Free Nucleic AcidsIBA 10/2023 - 04/2019
3	regorafenibIBA 01/2021 - 04/2017
3	SteroidsIBA 11/2020 - 04/2005
3	human ERBB2 proteinIBA 12/2018 - 03/2015
3	PlatinumIBA 01/2018 - 01/2005
3	Irinotecan (Camptosar)FDA LinkGeneric 01/2018 - 11/2013
3	DNA (Deoxyribonucleic Acid)IBA 06/2012 - 02/2010
2	ErbB Receptors (EGF Receptor)IBA 10/2023 - 03/2010
2	lenvatinibIBA 01/2023 - 04/2021
2	5- (2,4- dihydroxy- 5- isopropylphenyl)- 4- (4- morpholin- 4- ylmethylphenyl)isoxazole- 3- carboxylic acid ethylamideIBA 07/2022 - 12/2018
2	enzalutamideIBA 03/2022 - 09/2021
2	AnticoagulantsIBA 01/2022 - 03/2020
2	Phosphotransferases (Kinase)IBA 01/2022 - 04/2013
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2021 - 09/2021
2	Peptides (Polypeptides)IBA 01/2020 - 01/2019
2	Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)IBA 05/2017 - 06/2015
2	AntigensIBA 03/2011 - 06/2008
2	Cetuximab (Erbitux)FDA Link 03/2010 - 02/2010
1	Therapeutic UsesIBA 05/2024
1	Investigational DrugsIBA 05/2024
1	AntibodiesIBA 01/2024
1	Programmed Cell Death 1 ReceptorIBA 01/2024
1	B7-H1 AntigenIBA 01/2024
1	AfatinibIBA 10/2023
1	GSK2636771IBA 10/2023
1	TensinsIBA 10/2023
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 10/2023
1	ChromatinIBA 10/2023
1	ElectrolytesIBA 01/2023
1	tislelizumabIBA 01/2023
1	IntegrinsIBA 07/2022
1	Dalteparin (Dalteparin Sodium)FDA Link 01/2022
1	cabozantinibIBA 01/2022
1	pazopanib FDA Link 12/2021

Therapy/Procedure

37	Drug Therapy (Chemotherapy) 01/2023 - 12/2003
28	Therapeutics 05/2024 - 12/2003
11	Gastrectomy 11/2014 - 05/2007
7	Chemoradiotherapy 10/2022 - 11/2014
6	Esophagectomy 10/2022 - 11/2014
4	Adjuvant Chemotherapy 11/2023 - 11/2014
3	Drug Tapering 11/2023 - 11/2020
3	Radiotherapy 04/2021 - 12/2012
3	Combination Drug Therapy (Combination Chemotherapy) 01/2021 - 01/2003
3	Neoadjuvant Therapy 12/2020 - 06/2008
3	Stents 01/2014 - 07/2010
3	Self Expandable Metallic Stents 01/2014 - 07/2010
3	Lymph Node Excision (Lymph Node Dissection) 12/2012 - 09/2006
2	Induction Chemotherapy 04/2018 - 01/2017
1	Precision Medicine 05/2024
1	Liver Transplantation 01/2023